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10 Best Calming Products For Cats 2025 in the United States

#1

Winner

9.9 score

FELIWAY® Optimum 30 Day Cat Calming Refill for Pheromone Diffuser, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming

Type of Calming Product: Enhanced Calming Pheromone
Ingredients: Pheromone analogs
Duration of Effect: 30 days
Ease of Use: Plug into an open outlet
Safety and Side Effects: Safe for cats, humans, pets

Chosen by 1148 this week

FELIWAY® Optimum 30 Day Cat Calming Plug In Pheromone Diffuser Starter Kit, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming

Type of Calming Product: Diffuser with synthetic pheromones
Ingredients: Synthetic pheromones
Duration of Effect: Up to 30 days
Ease of Use: Plug in, replace monthly
Cat's Preferences: Varies by individual sensitivity
Safety and Side Effects: Drug-free, safe, no effect on others

Purina Pro Plan Veterinary Supplements Calming Care Cat Supplements - 30 ct. Box

Type of Calming Product: Powder
Ingredients: Bifidobacterium longum BL999, Vitamin E
Duration of Effect: Up to six weeks
Ease of Use: One packet daily
Cat's Preferences: Liver flavor
Safety and Side Effects: Safe use in pregnant animals unproven

FELIWAY Classic Cat Calming Pheromone Spray (60 mL)

Type of Calming Product: Spray
Ingredients: Natural feline pheromones
Ease of Use: Spray area 15 minutes before use
Cat's Preferences: 9/10 cats reduce urine spraying
Safety and Side Effects: No side effects, drug-free

COMFORT ZONE 6 Pack MultiCat Diffuser Refills; Cat Calming Pheromones Help Anxiety; 30-day refills

Type of Calming Product: Calming Diffuser Refills
Ingredients: Calming pheromones
Duration of Effect: 30 days per refill
Ease of Use: Easy to use
Safety and Side Effects: Meets Intertek safety, UL certified

Rocco & Roxie Cat Calming Treats with Melatonin for Cats, Stress and Anxiety Relief, Keep Calm for Grooming, Travel, or Vet Visits, Aid Sleep with Organic Ashwagandha and GABA, Chicken Flavored Chews

Type of Calming Product: Chews
Ingredients: melatonin, ashwagandha, GABA, tryptophan, theanine
Duration of Effect: temporary and situational
Ease of Use: daily use, 1 chew daily, more as needed
Cat's Preferences: chicken-flavored, crunchy shell, soft center
Safety and Side Effects: safe, vet recommended, no fillers, consult vet
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Our Top Picks

#1

Winner

FELIWAY® Optimum 30 Day Cat Calming Refill for Pheromone Diffuser, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming

Rating
9.9
Chosen by1,148
Duration of Effect
Ease of Use
Cat's Preferences

Most important from
11843 reviews

Duration of Effect
Improvement was noticeable within 48 hours of plugging in the diffuser.
Ease of Use
Optimum refills fit into regular diffusers, making it convenient to use.
Cat's Preferences
After plugging it in, our cat came out of hiding, ate, drank, and used the litter box within an hour.
Safety and Side Effects
Even though it's a bit messy, the relief it provided to our cat was worth every penny.

The FELIWAY Optimum Enhanced Calming Pheromone is a 30-day refill designed to reduce stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. As a non-sedating and drug-free solution, it releases pheromone analogs to provide a natural, reassuring message to cats, helping them feel more at ease. This product is easy to use—simply plug the diffuser into an open outlet with good air circulation, and it will work continuously for up to 30 days.

It’s important to use the FELIWAY diffuser with its specific refills for optimal results. One diffuser covers up to 700 square feet, and it should be replaced every six months, with refills changed monthly. Backed by over 25 years of research and recommended by vets, it’s a reliable choice for many cat owners.

However, it may not be universally effective for all cats, and the need to replace refills and diffusers regularly could be a recurring cost. Additionally, while it is safe for cats, humans, and other pets, it carries a specific scent (Mimosa) that may not appeal to everyone. This product is most beneficial for cat owners dealing with noticeable signs of feline stress in their homes.

Rating
9.9
Chosen by1,148
Duration of Effect
Ease of Use
Cat's Preferences

Most important from
11843 reviews

Duration of Effect
Improvement was noticeable within 48 hours of plugging in the diffuser.
Ease of Use
Optimum refills fit into regular diffusers, making it convenient to use.
Cat's Preferences
After plugging it in, our cat came out of hiding, ate, drank, and used the litter box within an hour.
Safety and Side Effects
Even though it's a bit messy, the relief it provided to our cat was worth every penny.
#2

Pet Honesty Calming Chews for Cats - Cat Anxiety Relief + Helps Reduce Stress - Behavioral Support & Promotes Relaxation for Travel, Boarding, Vet Visits, Separation Anxiety - Chicken (30-Day Supply)

Rating
9.8
Duration of Effect
Cat's Preferences
Ingredients

Most important from
22628 reviews

Duration of Effect
These chews deliver a noticeable calming effect within about an hour, significantly reducing aggressive behavior and nighttime restlessness linked to high testosterone levels.
Cat's Preferences
Cats find the chicken flavor irresistible, eagerly seeking out the chews even before they're given, making administration effortless.
Ingredients
The natural ingredients and allergen-free formula provide peace of mind for owners seeking a safe, additive-free calming aid.
Safety and Side Effects
Dose adjustments may be necessary to tailor the calming benefits to each cat's unique needs and reactions.
Ease of Use
Cats find the chicken flavor irresistible, eagerly seeking out the chews even before they're given, making administration effortless.

Pet Honesty Calming Chews for Cats are designed as tasty, easy-to-give treats that help reduce anxiety and promote relaxation in cats, especially during stressful events like travel, vet visits, or separation. They feature natural calming ingredients such as L-Theanine, L-Tryptophan, Chamomile, and Thiamine (Vitamin B1), which support the nervous system and help soothe anxious behavior. The chews come in a crunchy and creamy chicken flavor that many cats find appealing, making administration less challenging.

These chews are intended for all ages and medium breeds, with dosage based on the cat's weight, and can be given daily to maintain a calming effect over time. The product is made in the USA under strict safety standards, free from common allergens like corn, wheat, and soy, and contains no artificial additives, which supports its safety profile. The duration of the calming effect can vary between cats, and some cats might not respond to supplements as expected.

The product is well-rated by many users, although individual preferences for taste and texture may differ, so it might require some trial and error. This makes these chews a natural, convenient option for cat owners seeking to ease their pet’s stress with minimal fuss, especially if their cat enjoys flavored treats and needs support in mildly stressful situations.

Rating
9.8
Duration of Effect
Cat's Preferences
Ingredients

Most important from
22628 reviews

Duration of Effect
These chews deliver a noticeable calming effect within about an hour, significantly reducing aggressive behavior and nighttime restlessness linked to high testosterone levels.
Cat's Preferences
Cats find the chicken flavor irresistible, eagerly seeking out the chews even before they're given, making administration effortless.
Ingredients
The natural ingredients and allergen-free formula provide peace of mind for owners seeking a safe, additive-free calming aid.
Safety and Side Effects
Dose adjustments may be necessary to tailor the calming benefits to each cat's unique needs and reactions.
Ease of Use
Cats find the chicken flavor irresistible, eagerly seeking out the chews even before they're given, making administration effortless.
#3

FELIWAY® Optimum 30 Day Cat Calming Plug In Pheromone Diffuser Starter Kit, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming

Rating
9.7
Type of Calming Product
Duration of Effect
Ease of Use

Most important from
17570 reviews

Type of Calming Product
Strategic placement of diffusers in key areas prone to accidents or stress is essential to maximize the calming benefits.
Duration of Effect
Calming effects often become noticeable within a couple of weeks, especially when combined with other supportive measures like adjusting litter box setups.
Ease of Use
Using the diffuser as part of a broader strategy addressing environmental changes and health issues greatly enhances its success in reducing stress-related behaviors.
Cat's Preferences
Transformations in cat behavior can be dramatic, with previously territorial and anxious cats becoming relaxed enough to comfortably share spaces with other pets.

The FELIWAY Optimum diffuser uses synthetic pheromones designed to mimic natural calming signals cats give each other, making it a drug-free and non-sedating option. This makes it a good fit for cat owners looking for a safe, gentle way to reduce stress-related behaviors like spraying, scratching, and fearfulness. It works continuously for up to 30 days per vial, covering about 700 square feet, which suits most home environments with one or two diffusers. It’s simple to use—just plug into an outlet with some open space around it for best effect—and designed specifically for cats, so it won’t affect people or other pets. Users report significant reductions in common stress behaviors, which supports its effectiveness.

Because it relies on pheromones, results can vary from cat to cat depending on individual preferences and sensitivity. The diffuser must be replaced every six months and only with official FELIWAY refills, which adds some ongoing cost and limits flexibility with third-party products. Placement matters, too; it shouldn’t be hidden behind furniture or near litter boxes to work well.

While some cats respond quickly, others might take longer or need additional calming support. FELIWAY Optimum is a trusted, veterinarian-recommended calming product best suited for cat owners who want a safe, easy-to-use, and steady way to ease their cat’s stress without medication, though it requires monthly maintenance and careful placement for best results.

Rating
9.7
Type of Calming Product
Duration of Effect
Ease of Use

Most important from
17570 reviews

Type of Calming Product
Strategic placement of diffusers in key areas prone to accidents or stress is essential to maximize the calming benefits.
Duration of Effect
Calming effects often become noticeable within a couple of weeks, especially when combined with other supportive measures like adjusting litter box setups.
Ease of Use
Using the diffuser as part of a broader strategy addressing environmental changes and health issues greatly enhances its success in reducing stress-related behaviors.
Cat's Preferences
Transformations in cat behavior can be dramatic, with previously territorial and anxious cats becoming relaxed enough to comfortably share spaces with other pets.

Buying Guide for the Best Calming Products For Cats

Choosing the right calming product for your cat can make a significant difference in their overall well-being and behavior. Calming products can help reduce anxiety, stress, and unwanted behaviors in cats. When selecting a calming product, it's important to consider your cat's specific needs, preferences, and any underlying health conditions. Here are some key specifications to consider when choosing a calming product for your feline friend.
Type of Calming ProductCalming products for cats come in various forms, including sprays, diffusers, treats, collars, and supplements. The type of product you choose depends on your cat's preferences and the specific situation. For example, diffusers and sprays are great for creating a calming environment in your home, while treats and supplements can be useful for on-the-go calming. Collars provide continuous calming effects and are ideal for cats who are comfortable wearing them. Consider your cat's comfort and the context in which the product will be used to determine the best type for your needs.
IngredientsThe ingredients in calming products can vary widely, and it's important to choose products with safe and effective components. Common ingredients include pheromones, herbal extracts like chamomile and valerian root, and amino acids such as L-theanine. Pheromones mimic the natural calming signals cats produce, while herbal extracts and amino acids can help reduce anxiety. Always check the ingredient list for any potential allergens or substances that your cat may be sensitive to. If your cat has any health conditions or is on medication, consult your veterinarian before introducing new ingredients.
Duration of EffectDifferent calming products have varying durations of effect. For instance, sprays and diffusers may provide continuous calming effects for several hours to weeks, while treats and supplements may offer temporary relief for a few hours. Collars can last for up to a month. Consider how long you need the calming effect to last when choosing a product. For ongoing anxiety, a long-lasting solution like a diffuser or collar may be more appropriate, while short-term stressors like vet visits may be better managed with treats or sprays.
Ease of UseThe ease of use of a calming product can greatly influence your decision. Some products, like diffusers and collars, require minimal effort once set up, while others, like sprays and treats, may need to be administered more frequently. Consider your lifestyle and how much time you can dedicate to using the product. If you prefer a hands-off approach, a diffuser or collar might be the best choice. If you don't mind administering a product regularly, treats or sprays could be suitable.
Cat's PreferencesEvery cat is unique, and their preferences can play a significant role in the effectiveness of a calming product. Some cats may respond better to pheromone-based products, while others may prefer the taste of calming treats. Observe your cat's behavior and reactions to different types of products to determine what works best for them. It may take some trial and error to find the most effective solution, so be patient and attentive to your cat's needs.
Safety and Side EffectsSafety is paramount when choosing a calming product for your cat. Ensure that the product is specifically designed for cats and has been tested for safety. Be aware of any potential side effects, such as drowsiness or gastrointestinal upset, and monitor your cat closely when introducing a new product. If you notice any adverse reactions, discontinue use and consult your veterinarian. Always follow the manufacturer's instructions for use and dosage to ensure your cat's safety.

FAQ