10 Best Calming Products For Cats 2025 in the United States

The TherapetMD Cat Calming Diffuser is a plug-in pheromone diffuser designed to reduce anxiety and stress in cats, especially in multi-cat households. It uses a natural, vet-recommended dual-pheromone formula that mimics facial and maternal cat pheromones, helping to significantly cut down behaviors like urine spraying and scratching. One of its strengths is the 700 sq ft coverage area, making it suitable for larger rooms or shared spaces.

The diffuser works continuously once plugged in, with each refill lasting about 30 days, so it’s convenient and requires minimal effort from owners. It’s fragrance-free and safe for cats, humans, and other pets, which is important for households with multiple animals or sensitive individuals. Many users report noticeable improvements in reducing hiding, fear, and tension between cats, making it helpful during stressful events like vet visits or introducing new pets. It may take a few days to see the calming effects, and the low-glow indicator light might be hard to notice in bright settings, though this doesn’t affect the diffuser’s function.

Some cats may respond differently depending on their individual preferences, so results can vary. This diffuser provides a gentle, chemical-free way to create a calmer environment for anxious or stressed cats without hassle, although patience is needed to observe the full benefits.

Pet Honesty Calming Chews for Cats are designed as tasty, easy-to-give treats that help reduce anxiety and promote relaxation in cats, especially during stressful events like travel, vet visits, or separation. They feature natural calming ingredients such as L-Theanine, L-Tryptophan, Chamomile, and Thiamine (Vitamin B1), which support the nervous system and help soothe anxious behavior. The chews come in a crunchy and creamy chicken flavor that many cats find appealing, making administration less challenging.

These chews are intended for all ages and medium breeds, with dosage based on the cat's weight, and can be given daily to maintain a calming effect over time. The product is made in the USA under strict safety standards, free from common allergens like corn, wheat, and soy, and contains no artificial additives, which supports its safety profile. The duration of the calming effect can vary between cats, and some cats might not respond to supplements as expected.

The product is well-rated by many users, although individual preferences for taste and texture may differ, so it might require some trial and error. This makes these chews a natural, convenient option for cat owners seeking to ease their pet’s stress with minimal fuss, especially if their cat enjoys flavored treats and needs support in mildly stressful situations.

The Vetoquinol Zylkene Calming Supplement is designed to help small dogs and cats manage stress from situations like travel, vet visits, or loud noises. Its main calming ingredient, alpha-casozepine, comes from a milk protein, making it a natural option that avoids drowsiness or harsh side effects commonly seen in other calming products.

This supplement is lactose-free and gentle on sensitive stomachs, which is beneficial for cats with digestive sensitivities. The package contains capsules that you open and sprinkle over your pet’s food, making it straightforward to use daily. This daily routine can support behavioral issues and help your cat stay calm during stressful events.

With a solid positive rating from many users, Zylkene offers a safe, gentle, and easy-to-administer way to support your cat’s relaxation. Pet owners should monitor their cat’s response and ensure proper dosing.